High-Protein Tuna Salad Lettuce Cups

Featured in: Simple Suppers

This light and satisfying dish combines protein-rich tuna with creamy Greek yogurt and crisp vegetables, all nestled in butter lettuce cups. Ready in just 15 minutes with no cooking required, it's perfect for quick lunches or meal prep. The combination of lean protein, healthy fats, and fresh vegetables creates a balanced meal that keeps you full while supporting your health goals.

Updated on Wed, 11 Feb 2026 07:37:40 GMT
Freshly mixed High-Protein Tuna Salad Lettuce Cups topped with sliced avocado and cherry tomatoes on a plate. Save
Freshly mixed High-Protein Tuna Salad Lettuce Cups topped with sliced avocado and cherry tomatoes on a plate. | butterhollow.com

These High-Protein Tuna Salad Lettuce Cups are a fresh, protein-packed lunch option perfect for anyone seeking a light yet satisfying meal. By swapping traditional bread for crisp butter lettuce, this dish supports weight loss while providing 24g of protein per serving.

Freshly mixed High-Protein Tuna Salad Lettuce Cups topped with sliced avocado and cherry tomatoes on a plate. Save
Freshly mixed High-Protein Tuna Salad Lettuce Cups topped with sliced avocado and cherry tomatoes on a plate. | butterhollow.com

This American-style dish combines the creaminess of Greek yogurt and light mayonnaise with the sharp crunch of celery and red onion, all served in beautiful butter lettuce cups.

Ingredients

  • Tuna Salad
  • 1 (5 oz / 140 g) can tuna in water, drained
  • 2 tbsp Greek yogurt (nonfat or low-fat)
  • 1 tbsp light mayonnaise
  • 1 tsp Dijon mustard
  • 1 celery stalk, finely diced
  • 1/4 small red onion, finely diced
  • 1 tbsp fresh parsley, chopped
  • Juice of 1/2 lemon
  • Salt and pepper, to taste
  • Lettuce Cups & Toppings
  • 1 small head butter lettuce or romaine, leaves separated, washed and dried
  • 1/2 avocado, sliced (optional)
  • 8 cherry tomatoes, halved
  • 2 tbsp shredded carrots (optional)
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Instructions

Step 1
In a medium bowl, combine the drained tuna, Greek yogurt, mayonnaise, Dijon mustard, celery, red onion, parsley, and lemon juice. Mix well.
Step 2
Season the tuna salad with salt and pepper to taste.
Step 3
Arrange the lettuce leaves on a serving plate to form cups.
Step 4
Spoon the tuna salad evenly into the lettuce cups.
Step 5
Top each cup with avocado slices, cherry tomatoes, and shredded carrots if using.
Step 6
Serve immediately.

Zusatztipps für die Zubereitung

Using a mixing bowl and a spoon or fork, ensure the tuna is well combined with the yogurt and mustard for a smooth consistency. It is essential to drain the tuna thoroughly to prevent the lettuce cups from getting soggy.

Varianten und Anpassungen

For a dairy-free version, substitute Greek yogurt with a dairy-free alternative or use only light mayonnaise. For an extra flavor kick, add a pinch of smoked paprika or chili flakes to the tuna mixture.

Serviervorschläge

Serve these cups immediately with a fresh wedge of lemon on the side for extra brightness. They pair beautifully with additional shredded carrots or extra cherry tomatoes for added color and nutrients.

Vibrant butter lettuce cups filled with savory tuna salad, garnished with diced celery and a lemon wedge. Save
Vibrant butter lettuce cups filled with savory tuna salad, garnished with diced celery and a lemon wedge. | butterhollow.com
Vibrant butter lettuce cups filled with savory tuna salad, garnished with diced celery and a lemon wedge. Save
Vibrant butter lettuce cups filled with savory tuna salad, garnished with diced celery and a lemon wedge. | butterhollow.com
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With only 185 calories per serving, these High-Protein Tuna Salad Lettuce Cups are an excellent addition to any healthy meal plan, offering great flavor without the heavy carbs.

Kitchen Tips & Answers

How long does tuna salad last in the refrigerator?

The tuna salad mixture stays fresh for 3-4 days when stored in an airtight container in the refrigerator. For best results, keep the lettuce cups separate and assemble just before serving to prevent sogginess.

Can I make this dairy-free?

Yes, simply replace the Greek yogurt with additional light mayonnaise or a dairy-free yogurt alternative. The flavors will remain delicious and the texture stays creamy.

What type of lettuce works best for cups?

Butter lettuce and romaine are excellent choices because their leaves form natural cups. Iceberg lettuce also works well and provides extra crunch. Look for heads with large, intact leaves.

Can I use tuna packed in oil instead of water?

Yes, but you may want to reduce or omit the mayonnaise since oil-packed tuna adds more fat. Drain well and adjust the creamy ingredients to achieve your preferred consistency.

What can I substitute for celery?

Diced cucumber, bell peppers, or finely chopped radishes provide similar crunch. If you prefer no crunch, simply omit the celery—the other vegetables still provide plenty of texture.

Is this suitable for meal prep?

Absolutely! Store the tuna salad in one container and washed lettuce leaves separately. Both will keep for 3-4 days, making it easy to assemble fresh cups throughout the week.

High-Protein Tuna Salad Lettuce Cups

Fresh tuna salad with Greek yogurt and crisp lettuce cups. Ready in 15 minutes.

Prep duration
15 min
0
Complete duration
15 min
Created by Ella Thompson


Skill level Easy

Heritage American

Output 2 Portions

Eating preferences No gluten, Carb-Conscious

What you'll need

Tuna Salad

01 1 can (5 oz) tuna in water, drained
02 2 tablespoons Greek yogurt, nonfat or low-fat
03 1 tablespoon light mayonnaise
04 1 teaspoon Dijon mustard
05 1 celery stalk, finely diced
06 ¼ small red onion, finely diced
07 1 tablespoon fresh parsley, chopped
08 Juice of ½ lemon
09 Salt and pepper to taste

Lettuce Cups and Toppings

01 1 small head butter lettuce or romaine, leaves separated, washed and dried
02 ½ avocado, sliced, optional
03 8 cherry tomatoes, halved
04 2 tablespoons shredded carrots, optional

Method

Phase 01

Prepare the Tuna Salad Base: In a medium mixing bowl, combine the drained tuna, Greek yogurt, light mayonnaise, Dijon mustard, diced celery, diced red onion, fresh parsley, and lemon juice. Mix thoroughly until well incorporated.

Phase 02

Season to Taste: Adjust the tuna salad seasoning with salt and pepper according to personal preference.

Phase 03

Arrange Lettuce Cups: Place individual lettuce leaves on a serving plate, arranging them to form cup shapes for holding the tuna salad mixture.

Phase 04

Fill the Cups: Distribute the tuna salad evenly among the lettuce cups using a spoon.

Phase 05

Add Toppings: Garnish each lettuce cup with avocado slices, halved cherry tomatoes, and shredded carrots if desired.

Phase 06

Serve: Serve the lettuce cups immediately while the lettuce leaves remain crisp.

Kitchen tools needed

  • Medium mixing bowl
  • Spoon or fork
  • Sharp knife
  • Cutting board

Allergy details

Always review individual ingredients for potential allergens and seek professional medical guidance if uncertain.
  • Contains fish (tuna)
  • Contains egg (mayonnaise)
  • Contains dairy (Greek yogurt)
  • Check alternative brand labels for potential allergen cross-contamination

Nutrient breakdown per portion

Numbers shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 185
  • Fats: 7 g
  • Carbohydrates: 7 g
  • Proteins: 24 g