Pizza Roll Stuffed Garlic Knots

Featured in: Warm Bakes

Transform simple Greek yogurt dough into irresistible stuffed knots. Each rope encloses savory pepperoni and mozzarella before being tied into classic knot shapes. The golden exteriors get brushed generously with garlic butter immediately after baking, ensuring maximum flavor absorption. These protein-packed bites deliver 10 grams per serving while tasting completely indulgent.

Perfect for feeding crowds, they come together in just 40 minutes total. The self-rising flour creates pillowy texture while whey protein boosts nutritional value. Serve warm with marinara for dipping, or sprinkle extra parmesan and red pepper flakes for added kick.

Updated on Mon, 09 Feb 2026 10:02:00 GMT
Freshly baked Pizza Roll Stuffed Garlic Knots, golden and glistening with garlic butter, served warm with a side of marinara for dipping. Save
Freshly baked Pizza Roll Stuffed Garlic Knots, golden and glistening with garlic butter, served warm with a side of marinara for dipping. | butterhollow.com

My buddy texted me at 11 PM asking what I was bringing to Sunday's game, and I realized I'd promised homemade appetizers but had nothing ready. I was standing in my kitchen, staring at Greek yogurt and flour, when it hit me: what if I combined my high-protein dough obsession with pizza roll flavors? The first batch came out golden and ridiculous—so much better than store-bought that he texted the group chat before I even left my driveway. Now these garlic knots are my secret weapon whenever I need something that feels fancy but comes together faster than you'd think.

I made these for my brother's poker night last month, and watching six grown adults pause mid-conversation to eat their second knot was the kind of win that doesn't need words. Someone asked if they were from a bakery, and I got to say no with that smirk you only earn when something actually turns out.

Ingredients

  • Greek yogurt: The magic ingredient that keeps your dough tender without needing oil or excess fat—use plain nonfat or low-fat, because flavored yogurt will throw off the balance.
  • Self-rising flour: This does the heavy lifting for lift, but if you don't have it on hand, mix regular all-purpose flour with baking powder and salt as noted.
  • Whey protein powder: Unflavored is essential here, and it bumps up the protein content so these actually feel substantial, not like a guilty pleasure.
  • Garlic powder: Goes into the dough for a subtle base note that builds with the garlic butter finish.
  • Pepperoni: Buy the good stuff if you can—cheaper pepperoni gets smaller and harder when baked, but quality slices stay plump and flavorful.
  • Mozzarella and parmesan: Shred them fresh if possible; pre-shredded cheese has anti-caking agents that sometimes don't melt quite as smoothly.
  • Unsalted butter and fresh garlic: The garlic butter is your final flourish, so use real garlic cloves, not powder or jarred—it makes a noticeable difference in aroma and taste.
  • Fresh parsley: A small detail, but it adds color and a fresh note that keeps these from feeling heavy.

Instructions

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Mix your dough:
Combine Greek yogurt, self-rising flour, protein powder, garlic powder, and salt in a bowl until it comes together as a soft dough. Knead it briefly—just 30 seconds or so—until it's smooth; overworking makes it tough, and you want these knots tender.
Portion and shape:
Divide the dough into 12 equal pieces and roll each one into a 6-inch rope. The dough will feel slightly sticky, which is normal and actually helps with binding.
Fill and seal:
Flatten each rope slightly and lay 2 pepperoni slices down the center, then add a generous pinch of mozzarella and parmesan. Pinch the dough edges together to seal the filling completely so nothing leaks during baking.
Tie the knots:
Take each filled rope and gently tie it into a knot, tucking the ends underneath so they don't unravel. This step feels fiddly the first time, but it becomes almost meditative by the third knot.
Prep the pan:
Arrange all knots on a parchment-lined baking sheet, spacing them about an inch apart. Line them up and brush each one with half of your garlic butter mixture before baking.
Bake until golden:
Bake at 400°F for 18 to 20 minutes—they should be golden brown on top and firm to the touch. If you tap one, it should feel cooked through with just a slight give, not hollow.
Finish with garlic butter:
Pull them from the oven and immediately brush with the remaining garlic butter while they're hot so it soaks in. The warmth matters here; cold knots won't absorb the butter as richly.
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Twisted Pizza Roll Stuffed Garlic Knots reveal melty mozzarella and pepperoni filling on a rustic wooden board, perfect for game-day snacking. Save
Twisted Pizza Roll Stuffed Garlic Knots reveal melty mozzarella and pepperoni filling on a rustic wooden board, perfect for game-day snacking. | butterhollow.com

There's a moment after you pull these from the oven when the kitchen fills with garlic and melted cheese, and you realize you've accidentally created something that's now going to be expected at every gathering. That's not a bad problem to have.

The High-Protein Advantage

I started using Greek yogurt doughs because I was tired of appetizers that left me feeling sluggish halfway through an event. Adding protein powder transforms these from novelty knots into something that actually sticks with you, protein-wise. The combination gives you roughly 10 grams of protein per knot, so you're eating real food, not just empty carbs wrapped in cheese.

Flavor Tweaks That Actually Work

While these are perfect as written, I've experimented enough to know what elevates them without derailing the recipe. A light sprinkle of red pepper flakes before baking adds a subtle heat that makes people ask what the secret ingredient is. Swapping half the mozzarella for sharp cheddar creates a more complex cheese moment if you want deeper flavor. Dipping them in warm marinara keeps the Italian vibe alive and masks any slight dryness if they've been sitting for a few minutes.

Make-Ahead Strategy and Storage

You can assemble these up to 4 hours ahead, cover them loosely with plastic wrap, and bake when you're ready—they don't need rising time because the baking powder does its job instantly. Leftovers reheat surprisingly well in a 350°F oven for 5 minutes, though honestly, they rarely last long enough to test this. For freezing, place unbaked knots on a tray until solid, then transfer to a freezer bag; bake straight from frozen, adding just 2 to 3 extra minutes.

  • Assemble them in advance, but bake fresh for the best texture and that warm garlic butter moment.
  • Store cooled knots in an airtight container and reheat gently rather than eating them cold.
  • If you're bringing these somewhere, transport them warm in a covered container so they stay soft and the cheese stays melty.
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Close-up of Pizza Roll Stuffed Garlic Knots showing fluffy protein dough, melted cheese, and spicy pepperoni slices, brushed with parsley-flecked garlic butter. Save
Close-up of Pizza Roll Stuffed Garlic Knots showing fluffy protein dough, melted cheese, and spicy pepperoni slices, brushed with parsley-flecked garlic butter. | butterhollow.com

These knots have quietly become the thing people ask me to bring, and I've stopped pretending it's about the recipe and started admitting it's about that five-minute window when everything smells like a pizzeria and feels like a small victory. Make them once, and you'll understand why.

Kitchen Tips & Answers

Can I make these garlic knots ahead of time?

Prepare through step 6, arrange on baking sheet, cover tightly, and refrigerate up to 24 hours. Let sit at room temperature 15 minutes before baking. Brush with garlic butter just before placing in oven.

What can I use instead of pepperoni?

Turkey pepperoni works great for lighter versions. For vegetarian options, try sautéed mushrooms, spinach, sun-dried tomatoes, or bell peppers. Just ensure fillings aren't too watery to prevent soggy centers.

How do I store leftover stuffed knots?

Keep refrigerated in airtight container up to 3 days. Reheat in 350°F oven for 5-7 minutes until warmed through. Avoid microwaving as it makes the tough chewy. The garlic butter coating keeps them moist when reheated properly.

Can I freeze these before or after baking?

Freeze unbaked knots on baking sheet until firm, then transfer to freezer bags up to 1 month. Bake from frozen, adding 3-4 minutes to cooking time. Already baked knots freeze well too—reheat from frozen at 350°F for 10-12 minutes.

Why does my dough feel sticky or dry?

Humidity affects Greek yogurt consistency. If dough is too sticky, add flour 1 tablespoon at a time. If too dry, add 1 teaspoon yogurt. The protein powder also absorbs moisture differently between brands, so adjust accordingly until smooth and pliable.

What dipping sauces complement these knots?

Warm marinara is classic. Try pesto for basil freshness, ranch for cool contrast, or spicy arrabbiata for heat. Garlic aioli or melted cheese sauce work beautifully too. For game day, offer multiple dipping options for guests.

Pizza Roll Stuffed Garlic Knots

Golden garlic knots stuffed with cheese and pepperoni, brushed with buttery garlic glaze.

Prep duration
20 min
Heat duration
20 min
Complete duration
40 min
Created by Ella Thompson

Type Warm Bakes

Skill level Medium

Heritage American-Italian

Output 12 Portions

Eating preferences None specified

What you'll need

Protein Dough

01 1 cup Greek yogurt, plain, nonfat or low-fat
02 1 cup self-rising flour
03 1 scoop unflavored whey protein powder
04 1/2 teaspoon garlic powder
05 1/2 teaspoon salt

Filling

01 24 slices pepperoni
02 1 cup shredded mozzarella cheese
03 1/2 cup shredded parmesan cheese

Garlic Butter

01 4 tablespoons unsalted butter, melted
02 2 cloves garlic, minced
03 2 tablespoons chopped fresh parsley
04 1/4 teaspoon salt

Method

Phase 01

Preheat and Prepare: Preheat oven to 400°F. Line a baking sheet with parchment paper.

Phase 02

Mix Dough: In a large bowl, combine Greek yogurt, self-rising flour, protein powder, garlic powder, and salt. Mix until a soft dough forms and knead briefly until smooth.

Phase 03

Portion Dough: Divide dough into 12 equal pieces. Roll each piece into a 6-inch rope.

Phase 04

Fill Dough: Flatten each rope slightly and fill the center with 2 slices pepperoni and a generous pinch of mozzarella and parmesan cheese.

Phase 05

Form Knots: Pinch the dough to seal the filling, then gently tie each filled rope into a knot, tucking the ends underneath.

Phase 06

Arrange on Sheet: Arrange knots on the prepared baking sheet in a single layer.

Phase 07

Prepare Garlic Butter: In a small bowl, combine melted butter, minced garlic, parsley, and salt. Brush half of the garlic butter over the knots.

Phase 08

Bake: Bake for 18 to 20 minutes, until golden brown and cooked through.

Phase 09

Finish and Serve: Remove from oven and immediately brush with remaining garlic butter. Serve warm.

Kitchen tools needed

  • Mixing bowl
  • Spoon or spatula
  • Measuring cups and spoons
  • Baking sheet
  • Parchment paper
  • Pastry brush

Allergy details

Always review individual ingredients for potential allergens and seek professional medical guidance if uncertain.
  • Contains dairy: Greek yogurt, cheese, and butter
  • Contains gluten from wheat flour
  • May contain egg depending on protein powder selection
  • Contains pork from pepperoni

Nutrient breakdown per portion

Numbers shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 138
  • Fats: 6 g
  • Carbohydrates: 12 g
  • Proteins: 10 g