Creamy Pesto Penne Chicken

Featured in: Everyday Comforts

This dish features tender, bite-sized chicken pieces sautéed until golden and combined with al dente penne pasta. A rich sauce made from heavy cream, basil pesto, and grated Parmesan envelops the ingredients, delivering a luscious texture and vibrant flavors. Aromatic sautéed onion and garlic add depth, while fresh basil leaves and extra Parmesan enhance the finishing touch. Ideal for quick weeknight meals or casual gatherings, this creamy pesto penne with chicken balances richness and freshness beautifully.

Updated on Sat, 15 Nov 2025 10:53:00 GMT
Golden chicken and penne pasta swimming in creamy pesto sauce, a fantastic Creamy Pesto Penne & Chicken. Save
Golden chicken and penne pasta swimming in creamy pesto sauce, a fantastic Creamy Pesto Penne & Chicken. | butterhollow.com

A comforting Italian-inspired pasta dish featuring tender chicken, al dente penne, and a luscious creamy pesto sauce. Perfect for weeknight dinners or casual gatherings.

I first made this creamy pesto penne & chicken for a last-minute family dinner, and it quickly became a favorite. The kids especially love how the sauce clings to every bite of pasta.

Ingredients

  • Poultry: 2 boneless skinless chicken breasts (about 400 g) cut into bite-sized pieces
  • Pasta: 350 g penne pasta
  • Dairy: 200 ml heavy cream
  • Dairy: 40 g grated Parmesan cheese
  • Pesto: 80 g basil pesto (store-bought or homemade)
  • Vegetables: 1 small onion finely chopped
  • Vegetables: 2 cloves garlic minced
  • Pantry: 2 tbsp olive oil
  • Pantry: Salt and freshly ground black pepper to taste
  • Garnish (optional): Fresh basil leaves
  • Garnish (optional): Extra grated Parmesan

Instructions

Cook pasta:
Cook penne pasta in a large pot of salted boiling water until al dente according to package instructions. Drain and reserve 100 ml pasta water.
Prepare chicken:
Heat olive oil in a large skillet over medium-high heat. Add chicken pieces season with salt and pepper and sauté for 5–6 minutes until golden brown and cooked through. Remove and set aside.
Cook vegetables:
In the same skillet add chopped onion and cook for 2–3 minutes until softened. Add minced garlic and sauté for 30 seconds until fragrant.
Make sauce:
Reduce heat to medium. Pour in heavy cream and bring to a gentle simmer. Stir in pesto and Parmesan cheese mixing until smooth.
Combine chicken and sauce:
Return cooked chicken to skillet and toss to coat in sauce.
Add pasta:
Add drained penne to skillet tossing to combine. Use reserved pasta water as needed for desired sauce consistency.
Finish and serve:
Season with additional salt and pepper to taste. Serve immediately garnished with fresh basil and extra Parmesan.
A vibrant bowl of Creamy Pesto Penne & Chicken, showcasing the rich, cheesy pesto and tender chicken pieces. Save
A vibrant bowl of Creamy Pesto Penne & Chicken, showcasing the rich, cheesy pesto and tender chicken pieces. | butterhollow.com

Whenever I serve this dish the table always feels extra festive. Everyone asks for seconds and the fresh basil on top is always the first to disappear.

Required Tools

Large pot large skillet chef knife cutting board wooden spoon or spatula colander

Allergen Information

Contains dairy (cream Parmesan) wheat (pasta) and nuts (if pesto contains pine nuts). Always check pesto ingredients for potential allergens.

Nutritional Information (per serving)

Calories: 620 Total Fat: 27 g Carbohydrates: 58 g Protein: 36 g

Imagine the flavors: this Creamy Pesto Penne & Chicken boasts perfectly cooked pasta with basil-infused cream. Save
Imagine the flavors: this Creamy Pesto Penne & Chicken boasts perfectly cooked pasta with basil-infused cream. | butterhollow.com

This pasta is delicious both freshly served or reheated the next day. Bright basil and creamy sauce make every bite special.

Kitchen Tips & Answers

How do I achieve the perfect al dente penne?

Cook the penne in well-salted boiling water according to package timing, usually 10-12 minutes, until it offers a slight bite without being too soft. Drain carefully and reserve some pasta water to adjust sauce consistency.

Can I use homemade pesto instead of store-bought?

Absolutely! Homemade pesto with fresh basil, pine nuts, Parmesan, garlic, and olive oil will add a vibrant and fresh flavor that enhances the sauce beautifully.

What’s the best way to keep chicken tender and juicy?

Cut chicken into bite-sized pieces and sauté over medium-high heat until golden and cooked through, about 5-6 minutes, without overcrowding the pan to ensure even cooking.

How can I adjust the sauce thickness?

Use reserved pasta water to loosen the creamy pesto sauce gently while stirring, achieving the desired consistency without thinning out the flavor.

Are there good substitutes for heavy cream in the sauce?

For a lighter texture, you can replace heavy cream with half-and-half or whole milk, though the sauce will be less rich and slightly thinner in consistency.

Creamy Pesto Penne Chicken

Tender chicken and penne pasta tossed in a smooth creamy pesto sauce with Parmesan and basil.

Prep duration
15 min
Heat duration
25 min
Complete duration
40 min
Created by Ella Thompson


Skill level Easy

Heritage Italian

Output 4 Portions

Eating preferences None specified

What you'll need

Poultry

01 2 boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 12 oz penne pasta

Dairy

01 ¾ cup heavy cream
02 ⅓ cup grated Parmesan cheese

Pesto

01 ⅓ cup basil pesto

Vegetables

01 1 small onion, finely chopped
02 2 cloves garlic, minced

Pantry

01 2 tablespoons olive oil
02 Salt and freshly ground black pepper, to taste

Garnish

01 Fresh basil leaves
02 Extra grated Parmesan cheese

Method

Phase 01

Cook the pasta: Boil penne in a large pot of salted water until al dente, according to package instructions. Drain, reserving ⅓ cup pasta water.

Phase 02

Sauté the chicken: Heat olive oil in a large skillet over medium-high heat. Season chicken pieces with salt and pepper, then sauté for 5 to 6 minutes until golden and cooked through. Remove from skillet and set aside.

Phase 03

Cook aromatics: In the same skillet, cook chopped onion for 2 to 3 minutes until softened. Add minced garlic and sauté for 30 seconds until fragrant.

Phase 04

Prepare the sauce: Reduce heat to medium. Pour in heavy cream and bring to a gentle simmer. Stir in basil pesto and grated Parmesan until sauce is smooth.

Phase 05

Combine chicken and sauce: Return cooked chicken to the skillet and toss to coat in the creamy pesto sauce.

Phase 06

Finish the dish: Add drained penne to the skillet and mix well. Add reserved pasta water as needed to loosen the sauce. Adjust seasoning with salt and pepper.

Phase 07

Serve: Transfer to plates and garnish with fresh basil leaves and extra Parmesan cheese as desired.

Kitchen tools needed

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Colander

Allergy details

Always review individual ingredients for potential allergens and seek professional medical guidance if uncertain.
  • Contains dairy and wheat; pesto may contain nuts such as pine nuts.

Nutrient breakdown per portion

Numbers shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 620
  • Fats: 27 g
  • Carbohydrates: 58 g
  • Proteins: 36 g